WebHypergranular promyelocytic leukemia: correlation between morphology and chromosomal translocations including t(15;17) ... were described as: ‘(a) abnormal promyelocytes with a Web22 okt. 2014 · Acute promyelocytic leukemia (APL) is a hematological emergency frequently associated with severe coagulation disturbances. The typical morphology shows abnormal, usually bilobed hypergranular promyelocytes. In some cases the cytoplasmic granules are so large or numerous that they completely fill the cell, obscuring the nuclear cytoplasmic …
Hypergranular acute promyelocytic leukemia. - American Society …
WebIt is characterized by an excess of abnormal hypergranular promyelocytes in the bone marrow and other hematopoietic organs, and chromosomal translocation t(15;17)(q22;q21) leading to fusion of the genes encoding promyelocytic leukemia protein(PML) and retinoic acid receptor alpha (RARα) to generate the PML-RARα oncoprotein [2 ]. WebUpon examination of bone marrow smear there were hypergranular promyelocytes, with abundant cytoplasm and round/oval nuclei, some of which presented abundant Auer Rods (Faggot cells). Report of bone marrow PCR showed t (15;17) (PML-RARA),bcr1,L-form. Download Image Share Image Views: 626 Downloads: 17 Size: 0.2 MB Related Images: … total chlorine good free chlorine low
(a) Abnormal promyelocytes (hypergranular acute promyelocytic …
Web1 jan. 2012 · Rectangular cytoplasmic bodies and round inclusions are found in some of hypergranular promyelocytes. May-Giemsa staining. Cytology. Bone marrow promyelocytes were strongly positive for Sudan black B, myeloperoxidase staining and naphthol AS-D chloroacetate staining and negative for alpha-naphthyl butyrate staining. Web9 nov. 2000 · A man age 48 years presented in September 1991 with APL. BM examination confirmed the diagnosis of hypergranular APL with 92% promyelocytes. Cytogenetic … WebHyper-granular promyelocytes: large cells with bilobed nucleus, cytoplasm parked with azurophilic granules. “Faggot” cells: atypical promyelocytes with numerous Auer roads. … total chlorogenic acids