Webcsaw (2014–present) performs differential binding analyses of ChIP-seq experiments. Developed and maintained by Aaron Lun. See the Bioconductor Newsletter article on An overview of the csaw package. diffHic (2015–present) performs differential interaction analyses of Hi-C experiments. Developed and maintained by Aaron Lun. CRAN R packages Webcsaw - workflow to incorporate input/control samples? 1. markus.ringner 10. @markusringner-10600. Last seen 6.9 years ago. We are currently using csaw to investigate differential binding in a set of ChIP-seq experiments. I have some samples for which the control/input samples are highly variable across the genome and I am …

The csaw Book - Bioconductor

WebSep 28, 2024 · Detection of differential binding sites using csaw This is an alternative workflow for detection of differential binding / occupancy in ChIP-seq data. In contrast to working with reads counted within peaks detected in a peak calling step (as in the earlier example with DiffBind), this approach uses a sliding window to count reads across the … the range chicken run

csaw: a Bioconductor package for differential binding

WebApr 22, 2024 · csaw is a flexible R package, originally designed for ChIP-seq analysis, which accepts sorted BAM files for DA quantification via edgeR quasi-likelihood methodology following any one of numerous implemented normalization methods to address many biological scenarios [28, 30]. WebNov 17, 2015 · csaw can be used with an y type of ChIP-seq data, regard- less of the protein target or w hether sequencing is single- or paired-end. csa w does not require genomic annotation. WebNov 17, 2015 · csaw takes a set of sorted and indexed BAM files as input, where each file contains aligned reads for one ChIP-seq sample. Either single- or paired-end sequencing data can be accommodated. To avoid any assumptions about the shape or scope of the DB events, csaw implements a window-based approach to quantify read coverage across … the range christmas ornaments