Btg2 proliferation

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August undefined, 2024

WebBTG2 stimulates mRNA deadenylation via CAF1 activation through interaction with PABPC1. Interaction of BTG2 with the first RRM domain of PABPC1 is required for … WebApr 3, 2024 · To further confirm the effects of Btg2 deletion on glial cell proliferation in vitro, we performed BrdU incorporation assays in mixed glial cells derived from wild-type and Btg2 −/− mice. To mimic the pro-inflammatory conditions during cerebral hypoperfusion, mixed glial cells were treated with or without inflammatory stimuli (LPS and IFNγ ...

Transcriptomic Analyses Reveal B-Cell Translocation Gene 2 as a ...

WebMar 8, 2024 · BTG2 maps within the chromosomal segment (1q32), 10 and belongs to the BTG/TOB gene family that regulates cell cycle, cell proliferation, differentiation, and apoptosis. 9,45,46 BTG2 is described as an immediate early gene 47,48 and regulated by p53 activation. 12 Previous studies have reported low expression of BTG2 in a variety of … WebBTG2基因含有p53野生型基因的反应元件[11]，p73和p53可诱导与人类具有同源性的BTG2基因[12]。利用高密度芯片技术对基因的表达趋势进行研究，发现BTG2基因对细胞的分化、增殖和凋亡起调节作用[13]。 cheapest car insurance charlotte nc

Entry - *601597 - B-CELL ANTIPROLIFERATION FACTOR 2; BTG2 …

WebFeb 19, 2013 · BTG2 can regulate p53-induced anti-proliferation in tumor cells through the Ras signaling pathway and thus acts as a tumor suppressor . BTG2 may receive … WebSep 16, 2024 · The BTG2 gene was isolated in the rat by Bradbury et al. (1991) as an immediate early gene induced by nerve growth factor (NGF; 162030) in pheochromocytoma cells that undergo neural differentiation in the presence of NGF.The gene was called PC3 for pheochromocytoma cell-3. Its induction was independent of new protein synthesis as it … WebMigration and invasion enhancer 1 (MIEN1/C35/C17orf37), as an oncogenic gene, is located on chromosome 17q12 and 505 nucleotides from the 3′ end of the ERBB2 oncogene [1,2].Several studies have shown that MIEN1 overexpression results in either disease progression or metastatic propensity in many tumor types, including colon, prostate, … cvec chippewa falls

Deletion of B-cell translocation gene 2 (BTG2) alters the responses …

BTG2 gene predicts poor outcome in PT-DLBCL JIR

WebFigure 5 BTG2 inhibited ovarian cancer proliferation through the AKT and ERK-MAPK signaling pathway. (A) Protein levels of Cyclin D1, CDK4, Cyclin E1 and CDK2 were determined by Western blot on the left side. The ratios of Cyclin D1, CDK4, Cyclin E1, CDK2, were relative to β-actin and normalized to non-treated control group on the right … WebThe growth and development of oocyte affect the functional activities of the surrounding somatic cells. These cells are regulated by various types of hormones, proteins, metabolites, and regulatory molecules through gap communication, ultimately leading to the development and maturation of oocytes. The close association between somatic cells and oocytes, … cvec cash bidsWebThis study investigates the expression of micro-ribonucleic acid-21 (miRNA-21) and B cell translocation gene 2 (BTG2) in lung cancer cells. We examined the impact of miRNA-21 on biological characteristics of lung cancer cells, such as growth, proliferation, apoptosis, and invasion. The expression of … cvecara infinity

"WebBTG2 treatment exhibited inhibitory effect on PI3K/Akt pathway in MCF-7/ADR cells. Significance miR-27a-3p might be associated with resistance of breast cancer cells to adriamycin treatments, modulating cell proliferation and apoptosis by targeting BTG2 and promoting the PI3K/Akt pathway in breast cancer cells. miR-27a-3p/BTG2 axis might be … " - Btg2 proliferation

Btg2 proliferation

Genomic landscape of follicular lymphoma across a wide spectrum …

Webwww.ncbi.nlm.nih.gov WebA functional and biochemical interaction of TIS21(/BTG2/PC3) with Forkhead box M1 (FoxM1), essential transcription factor for hepatocyte regeneration and a master regulator of mitotic gene expression, was explored. ... Forced expression of TIS21 impaired growth, proliferation, and tumorigenic potential of Huh7 cells. At the mechanistic level ...

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WebMar 30, 2024 · Aberrations in FAS and PTEN co-occurred significantly (Q < 0.05), and a significant co-occurrence between PIM1, CD79B, and BTG2 (Q < 0.1) was found, especially in cases that relapsed early (Supplementary Figures S4-S5). WebFeb 25, 2024 · In this study, we established that hsa_circ_0069382 regulates the expression of BTG2/FAK by sponging miR-15a-5p, thus affecting the proliferation, invasion, and migration of gastric cancer. …

WebSep 14, 2024 · The overexpression of BTG2 in A549 cells causes cellular G1 phase arrest but did not affect cell proliferation, accompanied by increased activation of NF-κB. Our data indicate that BTG2 overexpression may trigger an autoregulatory prosurvival NF- κ B pathway, which is resistant to environmental intervention owing to an increased level of … WebApr 7, 2024 · BTG2 is expressed at low levels in multiple cancers and might therefore act as a tumor suppressor. 25 , 26 , 27 BTG2 plays an important role in cell proliferation, migration, invasion and drug resistance. 28 , 29 Little research has been performed on the biological behavior of BTG2 in response to IR stress.

WebOct 13, 2024 · B-cell translocation gene 2 (BTG2) is a crucial regulator in GLP-1-induced insulin gene expression and insulin secretion via upregulation of pancreatic duodenal homeobox-1 (PDX-1) in pancreatic beta-cells. These findings demonstrate the gonadotropin stimulation of Btg2 in the ovary and, the physical interaction of Btg2 with Ant2 in … WebThe closest homolog of BTG1 is BTG2, which also controls the proliferation and differentiation of adult neural stem cells; the role of BTG2, however, appears to differ from that of BTG1 being probably more relevant in controlling the terminal differentiation of neural stem and progenitor cells in the adult neurogenic niches.

WebMar 13, 2024 · Hwang et al. report that the transcription factors BTG1 and BTG2 are selectively expressed in quiescent T cells. In mice, T cells conditionally knocked out for both factors showed enhanced proliferation and a lowered threshold of activation both in vitro and in response to Listeria monocytogenes infection. Deficiency of BTG1 and BTG2 …

WebThus, the mutation of BTG2 may result in the dysfunction of tumor-repressor role of BTG2, and thereby contribute to malignant proliferation of B-cells in PT-DLBCL. In addition, we observed that 24% of patients were mutated in PRDM1 and were associated with shorter OS ( P =0.040, Table 3 ). cheapest car insurance company in georgiaWebMar 6, 2012 · The objective of the study was to investigate the impact of the B cell translocation gene 2 (BTG2) on lung cancer cell growth, proliferation, metastasis, and other biological characteristics and to provide experimental evidence for the biological treatment of human lung cancer. A pcDNA3.1-BTG2 eukaryotic expression vector was … cvec chippewaWebJun 15, 2024 · Results: MEG3 was lowly expressed in HCC tissues and cells. Overexpression of MEG3 inhibits the proliferation, migration and invasion of HCC cells. MiR-544b can be sponged by MEG3, and overexpression of miR-544b reverses the anti-cancer effect of MEG3. We further confirmed that BTG2 gene is the target gene of miR … cheapest car insurance company florida cheapest car insurance company in arizonaWebMar 21, 2024 · BTG2 regulates hepatic glucose homeostasis via induction of orphan nuclear receptor Nur77 in diabetic mouse model. pro-apoptotic pathway of CRP-CD32-Nox2-p53 … cvec arrington vaWebMar 21, 2024 · BTG2 (BTG Anti-Proliferation Factor 2) is a Protein Coding gene. Diseases associated with BTG2 include Diffuse Large B-Cell Lymphoma Activated B-Cell Type … cve can be search at which websiteWebThe BTG2 expression is downregulated in many human cancers. It is an instantaneous early response gene and plays important roles in cell differentiation, proliferation, DNA … cheapest car insurance chicago il